Here's the list---Judi Michelsen jmichels@sacto.nu.edu Sylvia, this copy is in ASCII, but has been formatted to email specs,so it fits on the screen. ====================================================================== A LAYMAN'S SHORT CLASSIFICATION OF PSYCHOTHERAPEUTIC DRUGS ANTI-DEPRESSANTS Anti-depressants can be roughly categorized into five groups, depending upon their chemical structure and the way they work: 1) tricyclics and tetracyclics (TCA's); 2) monoamine oxidase inhibitors (MAOI's); 3) serotonin-specific reuptake inhibitors ( SSRI's); 4) sedatives and hypnotics (including barbituates and benzodiazepines); 5) miscellaneous. (1) Tricyclics and Tetracyclics: These, along with the MAOI's, are considered the classic antidepressant drugs; they are also effective in a wide range of other disorders, including panic disorder, generalized anxiety disorder, posttraumatic stress diso rder, obsessive-compulsive disorder, eating disorders, and pain disorder. Enuresis and ADHD are the most common established indications for the tricyclics in children. Side Effects: These drugs share a number of common side effects: the possibility of inducing manic episodes (especially in bipolar I patients), anticholinergic effects (dry mouth, constipation, blurred vision, and urinary retention), sedation, orthostat ic hypotension, fatigue, poor concentration, and dizziness. Some patients may also experience such symptoms as tachycardia and other cardiac arrythmias, psychomotor stimulation, allergic reactions, weight gain, and a variety of other less common sympt oms, such as insomnia, tremors, weakness, sweating, vomiting, nervousness, peripheral neuritis, atoxia, endocrinal effects, and changes in blood sugar concentration. In some cases decreased libido and sexual performance become a problem. In rare cases a patient may experience hallucinations, seizures, convulsions, or other esoteric symptoms such as black tongue, leucophenia, jaundice, esinophilia, purpura, or agranulocytosis. As a general rule, the side effects associated with this class of drugs are n ot severe, and will usually decrease with prolonged use. Dosages will vary according to age, body weight, health condition, and tolerance; dosages appearing below are the beginning dosages for the average child and adult per day, followed by the maximum dosage recommended. An asterisk (*) designates either an unknown dosage for a particular medicine, or that the medicine is not usually used in that category. Many of the medicines listed below could be included in more than one category of psychotherapeutic drugs; however, I have tried to arrange them under those headings for which they are most commonly used. Child Adult Generic Name Trade Name Dosage Dosage amitriptyline Elavil, Endep, Enden Tryptizol (not used in US) * 75-150mg amitriptyline + perphenazine (combo) Etrafon, Triavil * 75-150mg amitriptyline + chlordiazepoxide (combo) Limbitrol, Limbitrol DS * 75-150mg amoxapine Asendin do not use 100-400mg clomipramine Anafranil 25-100mg 25-250mg desipramine Norpramin, Pertofrane do not use 75-300mg dothiepin Prothiaden * 75-100mg doxepin Adapin, Sinequan 25-75mg 75-200mg imipramine Tofranil, Janimine, Tofranil-PM 25-75mg 75-200mg lofepramine Gamanil (not used in US) * 140-210mg maprotiline Ludiomil * 75-225mg mianserin (not used in USA) Bolvidon * * nortriptyline Pamelor, Ventyl, Aventyl Allegron (not used in US) 10-20mg 75-150mg protriptyline hydrochloride Vivactil * 15-60mg trimipramine Surmontil * 75-200mg (2) Monoamine Oxidase Inhibitors (MAOI's): These drugs are generally accepted as being equal in efficacy to other antidepressant drugs but are currently used less frequently because of the dietary precautions that must be followed (total avoidance of tyr amine-containing foods) and the interactions with numerous other medications. They are often used as an alternative for patients who do not respond to the tricyclics and tetracyclics, or in atypical depressions. In addition to depression, MAOI's are use d to treat bipolar disorder, panic disorder with agoraphobia, posttraumatic stress disorder, eating disorders, social phobia, and pain disorder. Side Effects: Among the more common adverse side effects are orthostatic hypotension, weight gain, edema, sexual dysfunction, insomnia, sweating, dizziness, blurred vision, weakness, drowsiness, and constipation. Occasionally a patient will experience m uscle pains, difficulty in urinating, myoclonus, or parathesia. Particular care must be taken not to ingest food containing appreciable amounts of tyramine (alcohol, especially beer and wines, broad beans, aged cheese, nuts, beef or chicken liver, orange pulp, canned figs, chocolate, yeast and yeast vitamin supplements, caffeine-containing products like coffee and colas, meat extracts, summer sausages, packaged soups, and pickled or smoked fish, poultry, or other meats), as they are likely to have a hype rtensive reaction that can be life-threatening. In addition, certain medicines must also be avoided, such as anesthetics (spinal or local) containing epinephrine, antiasthmatic medications, antihypertensives, antihistimines, diet pills, narcotics (such as Demerol), certain allergy medicines, APC or empirin compounds, L-Dopa or L-tryptophan, cold and hayfever preparations, sinus medicines, sympathomimetics, SSRI's, and the tricyclic and tetracyclic drugs. Child Adult Generic Name Trade Name Dosage Dosage brofaromine Consonar (not sold in US) * * chlorgyline * * * isocarboxazid Marplan * 10-30mg moclobemide Aurorix, Manerix (not sold in US) * * pargyline Eutonyl * * phenelzine Nardil * 15-90mg selegeline Eldepryl * 10mg tranylcypromine Parnate * 10-30mg (3) Serotonin-specific Reuptake Inhibitors (SSRI's): These drugs, along with the tricyclic and tetracyclic drugs and the MAOI's, are considered the major antidepressant drugs; they are also effective in a wide range of disorders, including bipolar I diso rder, dysthymic disorder, eating disorders, panic disorder, obsessive-compulsive disorder, and borderline personality disorder. Because they generally have fewer adverse side effects than other classes of antidepressants they are more widely prescribed; one SSRI, fluoxetine (Prozac), the least cardiotoxic of all antidepressants, has become the most widely prescribed antidepressant and is one of the top ten most prescribed drugs in the US. Side Effects: The most common adverse side effects involve the central nervous system and the gastrointestinal system; they include headache, nervousness, insomnia, drowsiness, anxiety, agitation, nausea, diarrhea, anorexia, and dyspepsia. More rarely p atients may experience sexual dysfunction or allergic reactions (rashes). These drugs are generally considered to well-tolerated, and some adverse symptoms may lessen or disappear with continued use. Child Adult Generic Name Trade Name Dosage Dosage citalopram (not sold in US) * * fluoxetine Prozac 20-60mg 20-80mg fluvoxamine Luvox * 50-300mg paroxetine Paxil * 20-50mg sertraline Zoloft * 50-200mg serzone ? * * (4) Sedatives and Hypnotics: This class includes the barbituates, which are among the first drugs to be used in clinical psychiatric treatment, being introduced in the US in 1903. One of the oldest sedative-hypnotic drugs still in use, chloral hydrate, has been used since 1869. Because of their high abuse potential and lower therapeutic index, the barbituates are now less commonly prescribed than the newer anxiolytic compounds, such as the benzodiazepines and buspirone, which are considered much safer. Four others of the class, carbamates, piperidinediones, cyclic ethers, and tertiary carbinols, are still available for use, but are used so rarely because of their high abuse potential and toxic effects, that they are not listed below. Side Effects: A high abuse potential is associated with these drugs, the barbituates in particular. Drowsiness, confusion, constipation, blurred vision, edema, vertigo, paradoxical dysphoria, hyperactivity, cognitive disorganization, lethargy, fatigue, headache, syncope, ataxia, and in rare cases, Stevens-Johnson syndrome, megaloblastic anemia, and osteopenia. Many of the adverse side effects are similar to those of the benzodiazepines. Child Adult Generic Name Trade Name Dosage Dosage amobarbital Amytal * 65-400mg aprobarbital Alurate * * butabarbital Butisol * 15-120mg chloral hydrate Noctec * * ethchlorvynol Placidyl * * L-tryptophan (not in use in US) * * mephobarbital Mebaral * 32-400mg methohexital Brevital * * nitrazepam Mogadon * * pentobarbital Nembutal * 32-120mg phenobarbital Luminal, Barbita, 1.3-2.25mg Solfoton per lb of 100-300mg body weight secobarbital Seconal * 15-600mg zolpidem Ambien * 10-20mg (5) Miscellaneous: These are the drugs that, because of their chemical properties or the way in which they work, do not fit in any of the other categories. The sympathomimetics are recognized as being effective in the treatment of depressive disorders in special populations, such as the medically ill. Other medications work independently as antidepressants, while others work as adjuvant (facilitator or enhancer) or to potentiate other antidepressant drugs; adjuvants are so indicated on the chart. Side Effects: Side effects vary depending upon the chemical composition of the compound. Bupropion, for example has very few serious side effects; they include headache, insomnia, upper respiratory complaints, nausea, restlessness, agitation, and irrit ability, but not the anticholinergic effects and orthostatic hypotension seen in many of the others. The only significant adverse effect from L-tryptophan is nausea, or, in very rare cases, hepatotoxicity. The most common adverse effects of lithium trea tment are gastric distress, weight gain, tremor, fatigue, and mild cognitive impairment. Nefazodone seems to be fairly benign, not displaying the sedation, orthostatic hypotension, and priapism that is seen in some others. Side effects of pindolol are u sually mild, the most common being male impotence, as with all beta-blockers. The sympathomimetics are usually associated with anxiety, irritability, insomnia, and dysphoria. When taking thyroid hormones, patients sometimes experience weight loss, palpit ations, nervousness, diarrhea, abdominal cramps, sweating, tachycardia, increased blood pressure, tremors, headache, and insomnia; osteoporosis may also occur with long-term treatment. Trazadone sometimes produces sedation, orthostatic hypotension, dizzi ness, headache, dry mouth, and nausea. Occasionally gastric irritation occurs. Nausea, somnolence, dry mouth, dizziness, nervousness, constipation, asthenia, anxiety, anorexia, blurred vision, and sexual dysfunction were associated with venlafaxine. Child Adult Generic Name Trade Name Dosage Dosage bupropion Wellbutrin * 200-300mg dextroamphetamine Dexedrine * 2.5-60mg liothyronine (adjuvant) Cytomel * 25-50mg L-tryptophan (adjuvant) (not used in US) * 5-10mg lithium Eskalith, Lithane, (adjuvant) Cibalith-S, Lithobid, Lithonate, Lithotabs * 900-1800mg methylphenidate Ritalin 10-60mg 20-30mg nefazodone (not used in US) * * pemoline Cylert * 18.75-112.5mg pindolol Visken * 10-60mg thyroxine Levoxine, Levothroid, (adjuvant) Synthroid * * trazadone Desyrel * 150-600mg venlafaxin Effexor * 75-375mg ANXIOLYTICS Also called the "minor tranquilizers", the medicines in this group are primarily used in the treatment of anxiety; they are also used for some other disorders, such as depression, panic disorder, social phobia, bipolar I disorder, akathisia, and substan ce withdrawal. Because they have a higher therapeutic index and less abuse potential, the benzodiazepines (which comprise the largest number in this group) have largely replaced the barbituates in treatment for these disorders, and are also widely used a s sedatives and hypnotics as well as anesthetics, anticonvulsants, and muscle relaxants. Antihistimines are occasionally used to treat anxiety disorders, as are the beta-blockers. Side Effects: The most common adverse side effect of the benzodiazepines is drowsiness. Used over a long period of time, patients can build up a tolerance to them, and may suffer withdrawal symptoms when they discontinue use. Other less common side eff ects are dizziness, ataxia, and, rarely, mild cognitive deficits and allergic reactions. Serious adverse effects may be experienced when other sedative substances, like alcohol, are taken concurrently with the benzodiazepines. Buspirone may cause headac he, nausea, dizziness, and, rarely, insomnia. Occasionally a minor feeling of restlessness is associated with this drug. Clonidine may produce dry eyes and mouth, fatigue, sedation, dizziness, nausea, hypotension, and constipation. Some patients also e xperience sexual dysfunction. In rare cases, patients can experience insomnia, depression, nightmares, and hallucinations. Fluid retention can also become a problem if not treated with diuretics. The beta-blockers sometimes will result in hypotension, bradycardia, nausea, vomiting, diarrhea, and consitpation. Serious adverse reactions, such as agitation, confusion, and hallucinations, are rarely seen. It should be noted that some physicians find the anxiolitics to be very addictive; caution should be observed. Child Adult Generic Name Trade Name Dosage Dosage Alprazolam Xanax do not use .5-6mg Atenolol Tenormin * 50-100mg buspirone BuSpar * 15-60mg chlordiazepoxide Librium, Libritabs, Lipoxide 5-40mg 5-100mg clonazepam Klonopin 1.5-20mg 1.5-20mg (age 10 +) clonodine Catapres 5-25micrograms .2-2.4mg (for each 2.2 lbs) clorazepate Tranxene do not use under 9 7.5-60mg diazepam Valium, Valrelease, 3-10mg 2-60mg Zetran estazolam ProSom do not use 1-2mg ethyl alcohol Alcohol, Ethanol varies flumazenil Romazicon, Mazicon * 1-3mg (antagonist used in overdose of benzodiazepines) flunitrazepam Rohypnol, Hipnosedon (not used in US) * * flurazepam Dalmane do not use 15-30mg halazepam Paxipam 3-10mg 60-160mg hydroxyzine- hydrochloride Atarax 15-100mg 75-400mg hydroxyzine- Vistaril 15-100mg 75-400mg pamoate lorazepam Ativan, Alzapam do not use 2-6mg meprobamate Miltown (no longer used) * * meprobamate + benactyzine Deprol * * metoprolol Lopressor * 100-300mg midazolam Versed (used only by * 7.5-45mg anesthesiologists) (parenteral form only) naldolol Corgard * 40-240mg oxazepam Serax 3-10mg 30-120mg prazepam Centrax 3-10mg 20-60mg propranolol Inderal * 20-420mg quazepam Doral do not use 7.5-30mg temazepam Restoril do not use 15-30mg triazolam Halcion do not use .125-.5mg zolpidem Ambien do not use 10mg ANTIPSYCHOTICS This group, also known as the "major tranquilizers", or neuroleptics, is comprised mainly of a set of drugs known as dopamine-blockers, along with a few others that work in different ways to achieve the same ends. These drugs target the idiopathic psych oses that have no known cause, such as schizophrenia, schizophreniform disorder, schizoaffective disorder, delusional disorder, brief psychotic disorder, manic episodes, and major depressive disorder with psychotic features, as well as being commonly used in the treatment of patients who are severely agitated and violent. They have a wide application for a variey of disorders, including movement disorders, anxiety disorders, and psychoses that have organic causes. Side Effects: Potent drugs usually have potent side effects, and the antipsychotic drugs are no exception. Of the nonneurological adverse side effects associated with this class of drugs, cardiac effects may be the most dangerous; they have been hypothe sized to be a causal factor in sudden death to patients taking the drug, although this connection may be premature. Orthostatic hypotension, agranulocytosis, anticholinergic effects (described previously), nausea, vomiting, adverse endocrine effects, sex ual dysfunction, weight gain, allergic dermatitis, photosensitivity, irreversible pigmentation of the eyes, jaundice, muscle spasms, restlessness, tremors, vertigo, drowsiness, slurred speech, and bizarre dreams are some of the reported side effects. The neurological adverse effects associated with this group of drugs are potentially more serious; in fact, a whole separate group of medication-induced movement disorders has been included in the DSM-IV since their appearance. Among these effects that are neuroleptic-induced are parkinsonism, acute dystonia, acute akathisia, and occasionally, irreversible tardive dyskinesia. Neuroleptic malignant syndrome, which is life-threatening, has been reportedly connected with antipsychotic drug treatment, and epil eptogenic effects have also been observed in some cases. Sedation can also be a problem. Child Adult Generic Name Trade Name Dosage Dosage Dopamine-blockers: acetophenazine Tindal * 20mg butaperazine Repoise (not used in US) * * carphenazine Proketazine (not used in US) * * chlorpromazine Thorazine, Largactil (not used in US) 1.5-200mg 30-1000mg chlorprothixene Taractan * 50-400mg droperidol Inapsine, Droleptan (not used in US) * 30-60mg flupenthixol Depixol (not used in US) * 6-36mg fluphenazine Prolixin, Permitil, Modecate (not used in US) * 1-20mg haloperidol Haldol * 1-100mg loxapine Loxitane * 60-100mg mesoridazine Serentil * 30-400mg molindone Moban, Lidone * 50-100mg perphenazine Trilafon * 8-40mg pimozide Orap very low dosage 1-10mg piperacetazine Quide (not used in US) * * prochlorperazine Compazine, Stemetil (not used in US) 2.5-15mg 15-150mg promazine Sparine * 40-800mg remoxipride Roxiam (not used in US) * 200-400mg risperidone Risperdal * 4-8mg thioridazine Mellaril * 200-700mg thiothixene Navane do not use 6-60mg trifluoperazine Stelazine * 6-20mg triflupromazine Vesprin * 100-150mg zuchopenthixol Clopixol (not used in US) * 200-400mg Other antipsychotic drugs: carbamazepine Tegretol 200-1000mg 400-1200mg chlormethiazile Hemineverin (not used in US) * * clozapine Clozaril * 50-900mg fluspirilene Redeptin (not used in US) * 2-20mg lithium Eskalith * 900-1800mg (adjuvant) raclopride Dogmatil (not used in US) * * respirine Serpasil * * sulpiride Dolmatil, (not used in US) * 400-2400mg Sulpitil (not used in US) * 400-1800mg valproate Depakene * 250-1500mg MEDICATION-INDUCED MOVEMENT DISORDERS This rather inclusive group encompasses the anti-parkinsonsism, anticonvulsant, anticholinergic, side-effect medicines which target the neuroleptic-induced movement disorders, such as parkinsonism, malignant syndrome, acute dystonia, acute akathisia, tar dive dyskinesia, postural tremor and various other movement disorders that are extrapyramidal side effects (EPS). Included are the beta-adrenergic receptor antagonists (beta-blockers), the anticholinergics and amantadine, certain antihistamines, bromocri ptine, some of the benzodiazepines (see above), dantrolene, and L-dopa. Side Effects: Oddly enough, medicines that target side-effects can themselves have side-effects, such as hypotension and bradycardia, nausea, vomiting, diarrhea, and constipation with the beta-adrenergic receptor antagonists; anticholinergic effects (se e above), abuse potential, dizziness, insominia, irritability, depression, anxiety, ataxia, nausea, livedo reticularis (mostly the lower extremities), and, rarely, seizures, with the anticholinergics and amantadine; antihistamines are associated with seda tion, dizziness, and hypotension, and, occasionally, paradoxical excitement and agitation, poor motor coordination, epigastric distress, nausea, vomiting, diarrhea, constipation, dry mouth, urinary retention, blurred vision, and some abuse potential; brom ocriptine can result in nausea, headache, dizziness, vomiting, abdominal cramps, constipation, and, rarely, syncope or orthostatic hyptension, cardiac arrhythmias, and, very rarely (mostly in long-term and elderly patients), hallucinations, delusions, con fusion, and other behavioral changes; dantrolene may cause muscle weakness, drowsiness, dizziness, light-headedness, nausea, diarrhea, malaise, and fatigue, as well as speech disturbances, headache, visual disturbances, alteration of taste, depression, co nfusion, hallucinations, nervousness, insomnia, and, with long-term use, hepatitis, seizures, and pleural effusion with pericarditis; L-dopa is associated with abuse potential, nausea, vomiting, orthostatic hypotension, cardiac arrhythmias, and, with long -term use, abnormal involuntary movements and psychiatric disturbances, including psychosis, depression, and mania. Child Adult Generic Name Trade Name Dosage Dosage Beta-Adrenergic Drugs (Beta-blockers) atenolol Tenormin * 50-200mg atenolol + chlorthalidone Tenoretic * 50-200mg metoprolol Lopressor * 100-300mg nadolol Corgard * 40-240mg propranolol Inderal * 20-420mg Anticholinergics and Amantadine amantadine Symmetrel, Symadine * 200-300mg benztropine- Cogentin * .5-6mg mesylate biperidin Akineton * 2-6mg ethopropazine Parsidol * 100-200mg orphenadrine- Norflex, Dispal * 150-300mg citrate Biophan (not used in US) 150-300mg Norgesic, Norflex, (not used in US) * 60mg-? Disipal (not used in US) * 150-400mg procyclidine Kemadrin * 7.5-30mg trihexyphenidyl Artane, Tremin, Trihexane, Trihexy-5 * 6-15mg Antihistamines cyproheptadine Periactin 4-16mg 4-32mg diphenhydramine AllerMax, Banophen, Belix, Benadryl, Dephen Cough, Dormarex-2, Genahist, Hydramine, Nidryl, Nordryl, Nytol, Phendry, Sleep-Eze-3, Sominex 2, Twilite 37.5-100mg 75-200mg Bromocriptine bromocriptine Parlodel * 2.5-?mg Dantrolene dantrolene Dantrium * 4mg (per kg wt.)-10mg (per kg wt.) L-Dopa L-dopa (levodopa) Dopar, Larodopa * .5-8mg Miscellaneous bethanechol Urecholine * * phenytoin -------- * 200-600mg carbemazepine Tegretol * 100-800mg felbamate Felbatol 6.8-20.5mg 1200-3600mg (per lb wt.) MOOD STABILIZERS Many of the drugs that have already been discussed have been found to be efficacious in effecting mood regulation or stabilization, such as the benzodiazepines, carbamazepine, clozapine, the dopamine receptor antagonists, lithium, L-tryptophan, and valproate. Also included in this category are the calcium channel inhibitors or blockers, which are listed below. In addition, the lithium trade names associated with mood stabilization are listed below. Side Effects: The most common adverse side effects associated with the calcium channel inhibitors are hypotension, bradycardia, and AV heart block. Other symptoms include constipation, nausea, dry mouth, gastric distress, diarrhea, dizziness, headache, fatigue, and, occasionally, hyperactivity, akathisia, and parkinsonism. Child Adult Generic Name Trade Name Dosage Dosage diltiazem Cardizem * 120-360mg nifedipine Adalat, Procardia * 30-180mg nimodipine Nimotop * 120-240mg verapamil Calan, Isoptin * 120-480mg lithium carbonate Cibalith-S 900-1800mg Camcolt, Priadel, Liskonum, Phasal (these are not used in US) * 400-1200mg PSYCHOSTIMULANTS This category is devoted almost exclusively to the amelioration of attention-deficit/hyperactivity disorder (ADHD) effects. It includes the sympathomimetics, clonidine, and some of the tricyclic antidepressants. Side Effects: The symptoms associated with amphetamines, antidepressants, and clonidine have been discussed above; the sympathomimetics have been noted to cause anxiety, irritability, insomnia, dysphoria, decreased appetite, and, less commonly, movement disorders such as tics, Tourette's disorderlike symptoms, and dyskinesia. High dosages can cause dry mouth, pupillary dilation, bruxism, formication, and emotional lability, as well as a delusional disorder similar to paranoid schizophrenia. Child Adult Generic Name Trade Name Dosage Dosage amphetamine Benzedrine * * clonidine hydro- chloride Catapres .15-.3mg .2-2.4mg desipramine hydro- chloride Norpramin, Pertofrane 25-150mg 75-300mg dextroamphetamine Dexedrine 2.5-40mg * imipramine hydro- chloride Tofranil, Janimine 25-150mg 75-200mg methylphenidate Ritalin 2.5-60mg 20-60mg pemoline Cylert 18.75-112.5mg 37.5-112.5mg MISCELLANEOUS This is a catch-all category which includes the drugs that have effects and target symptoms that are not better-defined in the other lists; it includes medicines for alcohol withdrawal symptoms (disulfiram), opiod withdrawal (methadone and clonodine), Al zheimer's disease (tacrine), autistic disorder (fenfluramine), and sexual dysfunction (yohimbine). Side Effects: Use of disulfiram with alcohol, in extreme cases, can result in respiratory depression, cardiovascular collapse, myocardial infarction, convulsions, and death. Used without alcohol, it is sometimes associated with fatigue, dermatitis, impo tence, optic neuritis, a variety of mental changes, and hepatic damage. Methadone usage can induce tolerance, psychological dependence, and physical dependence, as well as dizziness, depression, sedation, euphoria, dysphoria, agitation, and seizures. In rare cases, delirium and insomnia have been reported with methadone use. Treatment with tacrine can result in significant elevations in hepatic transaminase levels, nausea, vomiting, diarrhea and other cholinergic symptoms, myalgia, and anorexia. Fenfl uramine may cause drowsiness, diarrhea, dry mouth, dizziness, confusion, incoordination, headache, elevated mood, depressed mood, anxiety, nervousness, tension, insomnia, weakness, fatigue, agitation, dysarthria, and altered libido. Use of yohimbine may result in elevated blood pressure and heart rate, increased psychomotor activity, irritability, tremor, headache, skin flushing, dizziness, urinary frequency, nausea, vomiting, and sweating. Child Adult Generic Name Trade Name Dosage Dosage disulfiram Antabuse * 125-500mg fenfluramine Pondimin * 1-1.5mg methadone Dolophine, Methadose * 15-40mg tacrine Cognex * 40-160mg yohimbine Yocon * 12-22.5mg ======================================================================